Neisseria gonorrhoeae & Neisseria meningitidis differentiation

 

 

 

Difference Between The Neisseria gonorrhoeae& Neisseria meningitidis

 

Neisseria gonorrhoeae :

Gonorrhea is a  common sexually transmitted disease caused by the bacterium, Neisseria Gonorrhea, which can be transmitted by during vaginal, anal, oral sex ,and at birth to a newborn.

 

 

Neisseria Meningitidis:

Neisseria meningitides is cause of epidemic cerebrospinal fever, clusters and sporadic cases of acute bacterial meningitides

It will be a meningococcal infection  

 

 

S.N.	Characteristics	Neisseria gonorrhoeae	Neisseria meningitides
1	Referred as	Referred to as gonococcus.	Referred to as meningococcus.
2	Agents	N. gonorrhoeae is the agent of gonorrhoea.	N. meningitidis is a major cause of cerebrospinal meningitis.
3	Vaccine Development	No	Serogroup A, B, C, Y and W-135 meningococcal infections can be prevented by vaccines.
4	Colony Morphology	N. gonorrhoeae form smooth, round, moist, uniform   grey/brown colonies with a greenish color underneath on primary isolation medium.	N. meningitides would form smooth, round, moist, uniform   large grey/brown colonies with a glistening surface and entire edges.
5	Morphology	N. gonorrhoea is kidney shaped with apposing ends concave.	N. meningitidis is semicircular diplococcus with flat apposing ends.
6	Autolyse	May autolyse	Autolyse
7	Maltose Fermentation	No	Yes
8	Nitrite Reduction	N. gonorrhoeae doesn’t reduce nitrites.	N. meningitidis can reduce nitrites in low concentrations.
9	Growth on Blood Agar	N. gonorrhoeae grow less   well on blood agar than N. meningitidis.	N.  meningitidis grow well on blood agar than N.  gonorrhoeae.
10	Capsule	No	Yes.  The capsule is anti-phagocytic and is an important virulence factor.
11	Site of Infection	Primarily causing infection of the anogenital tract.	Colonizes the upper respiratory tract as a commensal and occasionally invades to   cause systemic disease.
12	Pathogens	It is always considered a pathogen.	It is not always considered as pathogens.
13	Enzyme Production	It doesn’t produce gamma-glutamylaminotransferase.	It produces gamma-glutamylaminotransferase.
14	Specimen Collection	Transport swab of endocervix, urethra, rectum, pharynx, conjunctiva, blood, joint fluid, aspirates from skin lesions.	Collect cerebrospinal fluid (CSF) and blood, swab skin lesions and nasopharynx.
15	Β-Lactamase Production	Common	Rare
16	Movement	Movement of N. gonorrhoeae occurs at lower speed.	Movement of N. meningitidis occurred at higher speed and with a larger number of retracting pili.
17	Pili	N. gonorrhoeae most often moved using one retracting pilus.	N. meningitidis most often used four pili.
18	Prevalence and Mortality	N. gonorrhoeae infections have a high prevalence and low mortality	N. meningitidis infections have a low prevalence and high mortality.
19	Superbug	Considered as “superbug”	Not considered as “superbug”
20	Pathogenesis	N. gonorrhoeae can also cause conjunctivitis, pharyngitis, proctitis or urethritis, prostatitis, and orchitis.	Cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis.

 

 

 

 

 

STRUCTURE:

Neisseria gonorrhoeae:

 

Neisseria meningitidis: